Alzheimer’s disease and cerebral amyloid angiopathy are seen as a accumulation of amyloid\ (A) at the cerebrovasculature due to decreased clearance at the blood\brain barrier (BBB). failed to develop a high TEER, possibly caused by incomplete formation of tight junctions. We conclude that this hCMEC/D3 model has several limitations to study the cerebral clearance of … Continue reading Alzheimer’s disease and cerebral amyloid angiopathy are seen as a accumulation of amyloid\ (A) at the cerebrovasculature due to decreased clearance at the blood\brain barrier (BBB)